Kisspeptin-10 is the shortest fully bioactive fragment of the kisspeptin peptide family, encoded by the KISS1 gene. It functions as a high-affinity agonist at the KISS1R receptor and is the primary upstream regulator of GnRH secretion, making it a key compound in reproductive endocrinology and hormonal signalling research.
Available in 10mg | Lyophilised powder | ≥99% purity
£39.99
10 in stock
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Kisspeptin-10 (Tyr-Asn-Trp-Asn-Ser-Phe-Gly-Leu-Arg-Phe-NH₂) is the shortest fully bioactive fragment of the kisspeptin family, encoded by the KISS1 gene. Despite consisting of only ten amino acids, it retains the full receptor-binding potency of larger kisspeptin forms, making it well suited to targeted research applications.
It acts as a high-affinity ligand for the KISS1R receptor (GPR54) and serves as the primary upstream regulator of gonadotropin-releasing hormone (GnRH) secretion, placing it at the top of the hypothalamic-pituitary-gonadal (HPG) axis. Research has investigated its role in puberty onset, LH and FSH pulsatility, fertility signalling, and hormonal feedback. It has also been studied in cancer biology, where the KISS1 gene was originally identified as a metastasis suppressor. Supplied at ≥99% purity, HPLC verified. Intended strictly for research and laboratory use only.
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